VEGETOS: An International Journal of Plant Research & Biotechnology
(Society For Plant Research)

Research Articles

A SOCIETY FOR PLANT RESEARCH PUBLICATION


Volume: 34, Issue: 2, June 2021


Print ISSN : 0970-4078.
Online ISSN : 2229-4473.
Website:www.vegetosindia.org
Pub Email: contact@vegetosindia.org
Views: 117

Doi: 10.1007/s42535-021-00217-x
Doi Link: https://doi.org/10.1007/s42535-021-00217-x
First Page: 390
Last Page: 403
Published: 06 May, 2021

Human health risk assessment of essential and non-essential metals in vegetables (Jute Mallow, Onions, Celosia, Spinach and Tomatoes) from Ogun, Lagos and Oyo states, southwestern Nigeria


Abstract:

Vegetables are important sources of essential minerals and vitamins required for healthy living. However, contamination of vegetables with inorganic and organic substances may pose severe or irreversible health risk. The present study assessed the health risk of metals in vegetables from three states in southwestern Nigeria. A total of 180 vegetable samples (Jute Mallow, Onions, Celosia, Spinach and Tomatoes) were collected and analyzed for essential {copper (Cu), iron (Fe), nickel (Ni) and zinc (Zn)}, and nonessential {cadmium (Cd) and lead (Pb)} metals using the standard method. The health risk assessment was evaluated for hazard quotient (HQ), hazard index (HI) and cancer risk (CR). Results showed the highest concentrations of Fe in vegetable samples ranging from 4.9 mg kg−1 in jute mallow from Ogun to 558 mg kg−1 in spinach from Lagos. The spinach samples were more enriched in Fe and Zn than any other vegetables. The abundance pattern of metals in vegetables followed the order of Fe > Zn > Cu > Pb > Ni > Cd. The health risk assessment study revealed HQ and HI of metals greater than 1.0 in many vegetable samples indicating non-carcinogenic adverse health effects. The average CR values for Cd and Ni in vegetables were generally higher than the acceptable limit of 1.0 × 10–4, while the mean CR data for Pb were greater than the priority limit of 1.0 × 10–6. These CR values suggested possible cancer development through consumption of vegetables from the study area.

Vegetos

Keywords:


Vegetables, Health effects, Cancer, Metals, Risk


References:


  1. Abimbola W, Akindele S, Jokotagba O, Agbolade O (2015) Analysis of heavy metals in vegetables sold in Ijebu-Igbo, Ijebu North Local Government, Ogun State. Nigeria Inter J Sci Eng Res 6(11):130–136

  2. Aboyeji CM, Dunsin O, Daniel SD, Adekiya AO, Agbaje GO, Abolusoro SA (2016) An assessment of the levels of heavy metals, nitrates and nitrites in three leafy vegetables from selected rural and urban markets in Kwara State. Nigeria. Nig Food J 34(2):64–71

  3. Adedokun AH, Njoku KL, Akinola MO, Adesuyi AA, Jolaoso AO (2016) Potential human health risk assessment of heavy metals intake via consumption of some leafy vegetables obtained from four market in Lagos Metropolis. Nigeria J Appl Sci Environ Manag 20(3):530–539

  4. Adu AA, Aderinola OJ, Kusemiju V (2014) Assessment of trace metal levels in commonly edible vegetables from selected markets in Lagos State, Nigeria. Curr World Environ 9(3)

  5. Affum AO, Osae SD, Kwaansa-Ansah EE, Miyittah MK (2020) Quality assessment and potential health risk of heavy metals in leafy and non-leafy vegetables irrigated with groundwater and municipal-waste-dominated stream in the Western Region. Ghana Heliyon 6(12):e05829

  6. Akinnibosun FI, Adeola MO (2015) Quality assessment and proximate analysis of Amaranthus hybridus, Celosia argentea and Talinum triangulare obtained from open Markets in Benin City. Nigeria J Appl Sci Environ Manag 19(4):727–734

  7. Ali MH, Al-Qahtani KM (2012) Assessment of some heavy metals in vegetables, cereals and fruits in Saudi Arabian markets. he Egypt J Aqua Res 38(1):31–37

  8. AOAC (1995) Official Methods of Analysis, 16th edn. The Association Office Agricultural Chemists, Virginia

  9. Ashby HS (2002) Welding fume in the workplace. Profess Saf 47(4):55–63

  10. Atayese MO, Eigbadon AI, Adesodun J K. (2009) Heavy metal contamination of amaranthus grown along major highways in Lagos, Nigeria. Afri Crop Sci J 16(4)

  11. Ayantobo OO, Awomeso JA, Oluwasanya GO, Bada BS, Taiwo AM (2014) Non-cancer human health risk assessment from exposure to heavy metals in surface and groundwater in Igun-Ijesha, Southwest Nigeria. Am J Environ Sci 10(3):301–311

  12. Bedassa M, Abebaw A, Desalegn T (2017) Assessment of selected heavy metals in onion bulb and onion leaf (Allium cepa L.), in selected areas of central rift valley of Oromia region Ethiopia. J Hort 4:1–5

  13. Beetseh C, Onum D (2013) Chemical implications of metal toxicity of meat processed through tire fire. Chem Mat Res 3(10):79–89

  14. Dibofori-Orji AN, Edori OS (2015) Analysis of some heavy metals (Pb, Cd, Cr, Fe, Zn) in processed cassava flour (Garri) sold along the roadside of a busy highway. Arch Appl Sci Res 7(2):15–19

  15. Doherty VF, Sogbanmu TO, Kanife UC, Wright O (2012) Heavy metals in vegetables collected from selected farm and market sites in Lagos, Nigeria. Global Adv Res J Environ Sci Toxicol 1(6):137–142

  16. Duruibe JO, Ogwuegbu MO, Egwurugwu JN (2007) Heavy metal pollution and human biotoxic effects. Int J Phys 5:112–118

  17. Echem OG (2014) Determination of the levels of heavy metal (Cu, Fe, Ni, Pb and Cd) up take of pumpkin (Telfairia occidentalis) leaves cultivated on contaminated soil. J Appl Sci Environ Manag 18(1):71–77

  18. Elbagermi MA, Edwards HG, Alajtal AI (2012) Monitoring of heavy metal content in fruits and vegetables collected from production and market sites in the Misurata area of Libya. Inter Scholar Res Notice 2012

  19. enHealth (2012) Environmental health risk assessment-Guidelines for assessing human health risks from environmental hazards. D0702, 2012.www.health.gov.au. Accessed:10/01/18

  20. Fan Y, Zhu T, Li M, He J, Huang R (2017) Heavy metal contamination in soil and Brown Rice and human health risk assessment near three mining areas in Central China. J Health Eng. https://doi.org/10.1155/2017/4124302

  21. FAO/WHO (2001) Codex Alimentarius Commission. Food Additives and Contaminants, Joint FAO/WHO Food Standards Programme. 2001; ALINORM01/12A:1–289

  22. FAO/WHO (2004) Fruit and Vegetables for Health. Report of a Joint FAO/WHO Workshop, 1–3 September 2004, Kobe, Japan. http://www.fao.org/3/a-y5861e.pdf.

  23. FAO/WHO (2010) Joint FAO/WHO Expert Committee on Food Additives. Meeting, World Health Organization. (2010). Evaluation of Certain Food Additives: Seventy-first Report of the Joint FAO/WHO Expert Committee on Food Additives (Vol. 71). World Health Organization.

  24. FAO/WHO (2011) Codex Alimentarius Commission. Working document for information and use in discussions related to contaminants and toxins in the GSCTFF (Prepared by Japan and the Netherlands). Joint FAO/WHO food standards programme codex committee on contaminants in foods. The Hague, The Netherlands, 21 - 25 March 2011. CF/5INF/1.http://www.fao.org/tempref/codex/Meetings/CCCF/CCCF5/cf05_INF.pdf. Accessed 15 Jan 2019

  25. Farooq M, Anwar F, Rashid U (2008) Appraisal of heavy metal contents in different vegetables grown in the vicinity of an industrial area. Pak J Bot 40(5):2099–2106

  26. Galadima A, Garba ZN, Leke L, Almustapha MN, Adam IK (2011) Domestic water pollution among local communities in Nigeria-causes and consequences. Euro J Sci Res 52(4):592–603

  27. Guerra F, Trevizam AR, Muraoka T, Marcante NC, Canniatti-Brazaca SG (2012) Heavy metals in vegetables and potential risk for human health. Scientia Agricola 69(1):54–60

  28. Hanaa M, Eweida A, Farag A (2000) Heavy metals in drinking water and their environmental impact on human health. In International conference on environmental hazards mitigation, Cairo University, Egypt (pp. 542–556)

  29. Ibrahim AK, Salem A (2017) Content of Cd, Cr and Pb in Soil and Amaranthuscaudatus Grown in Yamaltu-Deba Local Government Area, Gombe State, Nigeria. Int J Plant Soil Sci16 (3): 1–8.

  30. IOM (Institute of Medicine) (2001) Dietary reference intakes for vitamin A, vitamin K, arsenic, boron, chromium, copper, iodine, iron, manganese, molybdenum, nickel, silicon, vanadium, and zinc. National Academy Press, Washington, DC, pp 442–501

  31. Islam MS, Ahmed MK, Habibullah-Al-Mamun M (2015) Determination of heavy metals in fish and vegetables in Bangladesh and health implications. Hum Ecol Risk Assess An Int J 21(4):986–1006

  32. Jacob JO, Kakulu SE (2012) Assessment of heavy metal bioaccumulation in spinach, jute mallow and tomato in farms within Kaduna Metropolis. Nigeria Am J Chem 2(1):13–16

  33. Jarup L (2003) Hazards of heavy metal contamination. Brit Med Bullet 68(1):167–182

  34. Jedy-Agba E, Curado MP, Ogunbiyi O, Oga E, Fabowale T, Igbinoba F, Osinubi P (2012) Cancer incidence in Nigeria: a report from population-based cancer registries. Cancer Epidemiol 36(5):e271–e278

  35. Juberg DR, Kleiman CF, Kwon SC (1997) Position paper of the American Council on Science and Health: lead and human health. Ecotoxicol Environ Saf 38(3):162–180

  36. Kaaber K, Menne T, Tjell JC, Veien N (1979) Antabuse treatment of nickel dermatitis. Chelation—a new principle in the treatment of nickel dermatitis. Cont Dermatol 5:221–228

  37. Kasozi KI, Otim EO, Ninsiima HI, Zirintunda G, Tamale A, Ekou J, Musoke GH, Muyinda R, Matama K, Mujinya R, Matovu H (2021) An analysis of heavy metals contamination and estimating the daily intakes of vegetables from Uganda. Toxicol Res Appl 5:2397847320985255

  38. Ketiku A (1976) The chemical composition of Nigerian onions (Allium cepa, linn). Food Chem 1(1):41–47. https://doi.org/10.1016/0308-8146(76)90013-3

  39. Kitata RB, Chandravanshi BS (2012) Concentration levels of major and trace metals in onion (Allium cepa L.) and irrigation water around Meki Town and Lake Ziway, Ethiopia. Bullet Chem Soc Ethiop 26(1):27–42.

  40. Kothadia JP, Arju R, Kaminski M, Mahmud A, Chow J, Giashuddin S (2016) Gastric siderosis: an under-recognized and rare clinical entity. SAGE Open Med 4:2050312116632109

  41. Labhade KR (2013) Assessment of heavy metal contamination in vegetables grown in and around Nashik City, Maharashtra State, India. IOSR J Appl Chem 5:9–14

  42.  

  43. Lawal AO, Audu AA (2011) Analysis of heavy metals found in vegetables from some cultivated irrigated gardens in the Kano metropolis, Nigeria. J Environ Chem Ecotoxicol 3(6):142–148

  44. Martirosyan DM, Miroshnichenko LA, Kulakova SN, Pogojeva AV, Zoloedov VI (2007) Amaranth oil application for coronary heart disease and hypertension. Lip Health Dis 6(1):1

  45. Nanven ND, Egila JN, Lohdip YN (2015) Heavy metal concentrations in some vegetables grown in a farm treated with urban solid waste in Kuru Jantar. Nigeria Brit J Appl Sci Technol 8(2):139–147

  46. National Research Council (1979) Iron. MD, University Park Press, Baltimore

  47. Ngole VM (2011) Using soil heavy metal enrichment and mobility factors to determine potential uptake by vegetables. Plant Soil Environ 57(1):75–80

  48. Ogunkunle CO, Ziyath AM, Adewumi FE, Fatoba PO (2015) Bioaccumulation and associated dietary risks of Pb, Cd, and Zn in amaranth (Amaranthus cruentus) and jute mallow (Corchorus olitorius) grown on soil irrigated using polluted water from Asa River. Nigeria Environ Monit Assess 187(5):1–7

  49. Olubanjo OO, Olanrewaju OO (2018) Impacts of Ogbese river irrigation on soil and vegetable (Celosia argentea) crops grown in Ogbese with Special Reference to Heavy Metals. Adv Res 14:1–9

  50. Oyebanji FF, Ogunyemi IA, Ojekunle ZO, Ogundipe O, Sosanya O, Aroyeun TH (2019) Heavy metal concentration and bacterial contamination associated with selected leafy vegetables in Abeokuta Metropolis, southwest Nigeria. Ife J Sci 21(1):109–119

  51. Plum LM, Rink L, Haase H (2010) The essential toxin: impact of zinc on human health. Int J Environ Res Pub Health 7(4):1342–1365

  52. PPRTV (2006) Provisional Peer Reviewed Toxicity Values for Iron and Compounds (CASRN 7439–89–6): Derivation of Subchronic and Chronic Oral RfDs. EPA/690/R-06/020F Final 9–11–2006.https://cfpub.epa.gov/ncea/pprtv/documents/IronandCompounds.pdf. Accessed:16 Jan 2019

  53. Rahman M, Islam MA (2019) Concentrations and health risk assessment of trace elements in cereals, fruits, and vegetables of Bangladesh. Biol Trace Elem Res 1–11

  54. Ramteke S, Sahu BL, Dahariya NS, Patel KS, Blazhev B, Matini L (2016) Heavy metal contamination of leafy vegetables. J Environ Protect 7:996–1004

  55. Ruel MT, Minot N, Smith L (2005) Patterns and determinants of fruit and vegetable consumption in sub-Saharan Africa: a multi -country comparison. WHO, Geneva

  56. Salawu K, Barau MM, Mohammed D, Mikailu DA, Abdullahi BH, Uroko RI (2015) Determination of some selected heavy metals in spinach and irrigated water from Samaru Area within Gusau Metropolis in Zamfara State. Nigeria J Toxicol Environ Health Sci 7(8):76–80

  57. Sobukola OP, Adeniran OM, Odedairo AA, Kajihausa OE (2010) Heavy metal levels of some fruits and leafy vegetables from selected markets in Lagos. Nigeria Afr J Food Sci 4(6):389–393

  58. Soghoian S, Sinert RH (2011) Heavy metals toxicity. Medscape. http://emedicine.medscape.com /article /814960-overview . Accessed 07 Dec, 2011

  59. Sokol RJ, Twedt D, McKim JM Jr, Devereaux MW, Karrer FM, Kam I, Neuschwander-Tetri BA (1994) Oxidant injury to hepatic mitochondria in patients with Wilson’s disease and Bedlington terriers with copper toxicosis. Gastroenterol 107(6):1788–1798

  60. Taiwo AM (2019) A review of environmental and health effects of organochlorine pesticide residues in Africa. Chemos 220:1126–1140

  61. Taiwo AM, Awomeso JA (2017) Assessment of trace metal concentration and health risk of artisanal goldmining activities in Ijeshaland, Osun State Nigeria— Part 1. J Geochem Explor 177:1–10

  62. Taiwo AM, Aluko EA, Babalola OO (2010) Investigations into the teratogenic potentials of lead in pregnant rabbit. Inter J Biol Chem Sci 4(3):809–814

  63. Taiwo AM, Arowolo TA, Adekunle IM, Adetunji MT (2013) Evaluating the environmental impacts of poultry farming on stream water quality: a Study from Abeokuta, Nigeria. Environ Qual Manag 22(4):79–93

  64. Taiwo AM, Beddows DCS, Calzolai G, Harrison RM, Lucarelli F, Nava S, Shi Z, Valli G, Vecchi R (2014) Receptor modelling of airborne particulate matter in the vicinity of a major steelworks site. Sci Tot Environ 490:488–500

  65. Taiwo AM, Awomeso JA, Taiwo OT, Oremodu BD, Akintunde OO, Ojo NO, Arowolo TA (2017) Assessment of health risks associated with road dusts in major traffic hotspots in Abeokuta metropolis, Ogun state, southwestern Nigeria. Stoch Environ Res Risk Assess 30:1–17

  66. Taiwo AM, Oyebode AO, Salami FO, Okewole I, Gbogboade AS, Agim C, Davidson N (2018) Carcinogenic and non-carcinogenic evaluations of heavy metals in protein foods from southwestern Nigeria. J Food Composit Anal 73:60–66

  67. Taiwo AM, Oyeleye OF, Majekodunmi BJ, Anuobi VE, Afolabi SA, Idowu OE, Ojekunle ZO, Taiwo OT (2019) Evaluating the health risk of metals (Zn, Cr, cd, Ni, Pb) in staple foods from Lagos and Ogun states, southwestern Nigeria. Environ Monit Assess 191(3):1–1

  68. Taiwo AM, Aigbodion CO, Ojekunle OZ, Akinhanmi TF (2020) Health risk assessment of metals in selected drinks from Abeokuta, Southwestern Nigeria. Biol Trace Elem Res 197:1–15. https://doi.org/10.1007/s12011-020-02029-7

  69. Tong S, Schirnding YEV, Prapamontol T (2000) Environmental lead exposure: a public health problem of global dimensions. Bull World Health Org 78:1068–1077

  70. Towolawi AT, Arowolo TA, Bada BS, Badejo AA, Taiwo AM (2017) Phytoextraction assessment of green Amaranth (AmaranthusviridisLinn.) grown on soil amended with sewage sludge. Ife J Sci 19 (1): 133–140.

  71. USEPA (2001) United States Environmental Protection AgencyRisk Assessment Guidance for Superfund: Process for conducting Probabilistic Risk Assessment (Part A); EPA 540-R-02-002; USEPA: Washington, DC, USA, Volume 3

  72. USEPA (2007) United States Environmental Protection Agency, Framework for Metal Risk Assessment, EPA 120-R-07–001, Washington DC, 2007

  73. Usman B, Ahmad A, Jibrin NA, Gayus EA, Jibrin M (2020). Bioaccumulation and human health risk of heavy metals from pesticides in some crops grown in Plateau State, Nigeria. Presented at the 1st International Electronic Conference on Plant Science 2020 Dec (Vol. 1, p. 15).

  74. WHO (1993) Evaluation of certain food additives and contaminants. In: Forty-First Report of the Joint FAO/WHO Expert Committee on Food Additives., WHO, Geneva, Switzerland. (WHO Technical Series, 837)

  75. WHO (1996) Iron in drinking-water. Background document for development of WHO Guidelines for Drinking-water Quality. World Health Organization, Geneva. WHO/SDE/WSH/03.04/08

  76. WHO (2015) Country Statistics, Nigeria.www.who.int/country/nga/en. Accessed 10 July, 16


  77.  


Acknowledgements :



The authors acknowledge the laboratory assistance of Mrs. E.O. Sorinola of the Department of Environmental Management, Federal University of Agriculture, Abeokuta, and Mr. S.A. Omosuli of the Department of Agronomy, University of Ibadan. The anonymous reviewers are kindly acknowledged for their constructive criticism.


Author Information:



Adewale M. Taiwo
Department of Environmental Management and Toxicology, Federal University of Agriculture, Ogun State, Abeokuta, Nigeria
taiwoademat2003@yahoo.com
Osayande J. Avan
Department of Environmental Management and Toxicology, Federal University of Agriculture, Ogun State, Abeokuta, Nigeria


Kofoworola A. Olatunde
Department of Environmental Management and Toxicology, Federal University of Agriculture, Ogun State, Abeokuta, Nigeria

Karimat L. Abdullahi
Department of Chemistry, Baze University, Abuja, Nigeria

Patricia K. Ogunkoya
Department of Environmental Management and Toxicology, Federal University of Agriculture, Ogun State, Abeokuta, Nigeria

Ebunoluwa R. Lawal
Department of Environmental Management and Toxicology, Federal University of Agriculture, Ogun State, Abeokuta, Nigeria

Al-Amin Adenekan
Department of Environmental Management and Toxicology, Federal University of Agriculture, Ogun State, Abeokuta, Nigeria

, Osayande J. Avan
Department of Environmental Management and Toxicology, Federal University of Agriculture, Ogun State, Abeokuta, Nigeria

Abibat O. Jimoh
Department of Environmental Management and Toxicology, Federal University of Agriculture, Ogun State, Abeokuta, Nigeria

Gbolahan Oladimeji
Department of Environmental Management and Toxicology, Federal University of Agriculture, Ogun State, Abeokuta, Nigeria




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