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Zohra Yousfi Fatima, Farid Bennabi, Fatna Moussi, Yasmine Khane, Walid Mohamedi Mohamed, Lahcen Belarbi, Djamila Boukraa, Khaled Rahmani, Ali Khalfa, Ech-Chergui Abdelkader Nebatti
Keywords: Silver nanoparticles, n Inula viscosan , Aqueous extract, Anti-inflammatory, Antibacterial, Antioxidant
Silver nanoparticles (AgNPs) were biosynthesized using an aqueous extract of Inula viscosa leaves. FTIR analysis indicated that the extract contains functional groups that aid in the reduction and stabilization of AgNPs. XRD confirmed the crystalline structure and an average size of 17.93 nm, with the presence of silver oxide. SEM and TEM analyses revealed spherical AgNPs sized between 25 and 50 nm. EDX analysis showed that the AgNPs are composed of 58.27% silver, along with traces of oxygen, carbon, chlorine, sodium, and sulfur. These findings suggest that I. viscosa extract is an effective medium for AgNP synthesis. The current study also explored the biological properties of the synthesized AgNPs, revealing significant antibacterial, antioxidant, and anti-inflammatory activities. The AgNPs exhibited notable anti-radical activity with an IC50 of 0.1815 mg/ml for DPPH degradation and an 87% inhibition of red blood cell hemolysis, comparable to Diclofenac. These results validate the traditional use of I. viscosa leaves for AgNP biosynthesis and highlight their potential for various applications in antimicrobial, antioxidant, and anti-inflammatory fields.
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