Anti-fungal, anti-oxidant and phytochemical analysis of Plumbago zeylanica L.

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Research Articles | Published:

Print ISSN : 0970-4078.
Online ISSN : 2229-4473.
Website:www.vegetosindia.org
Pub Email: contact@vegetosindia.org
Doi: 10.1007/s42535-020-00102-z
First Page: 247
Last Page: 257
Views: 639


Keywords: Medicinal properties, Inhibitory activities, Natural compounds, Free radicals, GC–MS analysis


Abstract

Free radicals play a major role in development of many human diseases like cancer etc. In the present investigation Plumbago zeylanica (Pz) was used for anti-fungal activity, anti-oxidant activity as well as phytochemicals investigation. Anti-fungal activities were determined against four pathogenic fungal species Fusarium oxysporum, Rhizoctonia solanii, Alternaria sp. and Sclerotium rolfsii. Anti-oxidant activity and phytochemical investigation were determined by standard method using spectrophotometer, gas chromatography and mass spectroscopy. The excellent inhibitory activities were observed against Alternaria spp. (98%), F. oxysporum (68%), R. solanii (97.5%) followed by S. rolfsii (93.4%) at 62.5 μg/ml. The P. zeylanica showed free radicals scavenging activity by DPPH method (77.8% inhibition at 1000 µg/ml), CUPRAC assay (0.07940 TE mM at 1000 µg/ml), Anthocyanin content (2.404 CGE mg/ml), Flavonoid content (55,330 GAE/g), Phenols (14.75 µg/ml), Alkaloids (54 mg/g), Saponins (3.95%) and Tannin (7 µg/10 ml). So P. zeylanica extracts can be used as a source of bio-fungicide and scavenger of free radicals.


Medicinal properties, Inhibitory activities, Natural compounds, Free radicals, GC–MS analysis


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Acknowledgements

We are thankful to Head and Dean University Department of Botany, Ranchi University, Ranchi and AIRF, JNU, New Delhi for providing all necessary facilities. We also acknowledge UGC for providing financial assistance under Major Research Project F. No. 42-955/2013 (SR).


Author Information

Jain Paras
Laboratory of Plant Physiology and Biotechnology, University Department of Botany, Ranchi University, Ranchi, India
paras.jain42@yahoo.in
Sharma H. P.
Laboratory of Plant Physiology and Biotechnology, University Department of Botany, Ranchi University, Ranchi, India


Singh Pallavi
Laboratory of Plant Physiology and Biotechnology, University Department of Botany, Ranchi University, Ranchi, India