Eco friendly synthesis of TiO2 nanoparticles using aqueous Ocimum americanum L. leaf extracts and their antimicrobial, anti-proliferative and photocatalytic activities

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Short Communications | Published:

Print ISSN : 0970-4078.
Online ISSN : 2229-4473.
Website:www.vegetosindia.org
Pub Email: contact@vegetosindia.org
Doi: 10.1007/s42535-020-00152-3
First Page: 805
Last Page: 810
Views: 1053


Keywords: Green synthesis, Ocimum americanum , TiO2 , Antimicrobial, Antiproliferative, Photodegradation


Abstract

Bio-synthesis of TiO2 nanoparticles was accomplished with Ocimum americanum L leaf extracts. The morphology, optical and functional properties of synthesized TiO2 nanoparticles were characterized by XRD, UV–Vis spectroscopy, FT-IR, and FE-SEM with EDAX respectively. The aqueous extracts of these nanoparticles were evaluated for its antimicrobial activities against Bacillus cereus, Clostridium perfringens, Salmonella paratyphi, Klebseilla pnemoniae, Candida albicans and Aspergillus niger using an agar well method. The antiproliferative activity was analyzed by MTT assay. Photocatalytic analysis against methylene blue dye was investigated. The biosynthesized TiO2 nanoparticles was analyzed by SEM with an average size of the particle was 25 nm. The synthesized TiO2 nanoparticles were exhibited excellent antimicrobial and antiproliferation activities against selected pathogens and human skin cancer cell line (431) respectively and expression of admirable photocatalytic activity with reduction of 91.1%. Based on the above studies, it is concluded that these nanoparticles are eco-friendly, inexpensive and pollution free material which can be applied for multifaceted environmental applications.


Green synthesis, Ocimum americanum , TiO2 , Antimicrobial, Antiproliferative, Photodegradation


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Acknowledgements

The authors are grateful to the DST-SERB (SB/YS/LS-109/2014) for providing financial assistance to this project. We sincerely express our thanks to the management of A.V.V.M. Sri Pushpam College (Autonomous), Poondi, for providing necessary facilities and support to carry out this work.


Author Information

Vijayakumar S.
Computational Phytochemistry Laboratory, PG and Research Department of Botany, AVVM Sri Pushpam College (Autonomous) Poondi, Thanjavur, India
svijaya_kumar2579@rediff.com
Vidhya E.
Computational Phytochemistry Laboratory, PG and Research Department of Botany, AVVM Sri Pushpam College (Autonomous) Poondi, Thanjavur, India


Anand G. Chinnu
Computational Phytochemistry Laboratory, PG and Research Department of Botany, AVVM Sri Pushpam College (Autonomous) Poondi, Thanjavur, India


Nilavukkarasi M.
Computational Phytochemistry Laboratory, PG and Research Department of Botany, AVVM Sri Pushpam College (Autonomous) Poondi, Thanjavur, India


Punitha V. N.
Computational Phytochemistry Laboratory, PG and Research Department of Botany, AVVM Sri Pushpam College (Autonomous) Poondi, Thanjavur, India

Sakthivel B.
PG and Research Department of Physics, AVVM Sri Pushpam College (Autonomous) Poondi, Thanjavur, India