Thaniarasu Raja, Abirami Srinivasan, Kumar Thiruppathi Senthil, Rao Mandali Venkateswara
Keywords:
Plectranthus bourneae
, Antibacterial activity, Phytochemicals, Antioxidant activity
The present investigation focuses on phytochemical screening and biological activities of Plectranthus bourneae, a medicinal plant species. Various solvents or ethanolic extract of leaf was used to investigate the phytochemicals by qualitative and quantitative methods, GC-MS, FTIR, and antioxidant activities. Qualitative phytochemical analysis of leaf extracts showed the presence of alkaloids, carbohydrates, saponins, glycosides, phytosterols, resins, phenols, tannins, diterpenes, flavonoids, proteins and amino acids. The highest concentrations of total phenolic content (50.10 ± 1.84 mg GAE/g) and tannins (83.03 µg/ml) was observed in ethanolic extracts. GC-MS results revealed the presence of various phytocompounds which are greatly known for their biological activities. The results of FTIR spectra confirmed the presence of different functional groups with peaks at 3347.74 cm− 1 (alcohols, phenols) and 2924.23 cm− 1 (alkanes). The free radical scavenging activity of the ethanolic leaf extract was found to be high in DPPH (441.27 µg/ml) and hydroxyl radicals (22.4–74.4% at the concentration of 1000 µg/ml) scavenging assays.
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The authors R. Thaniarasu and S. Abirami acknowledge the Department of Botany, Science campus, Alagappa University, Karaikudi, for providing lab facilities (RUSA-2.0 [F.24/51/2014-U]), infrastructure support to conduct the research work. T. Senthil Kumar and M.V. Rao are thankful to University Grants Commission, New Delhi for financial support in the form of major research project (UGC REF. NO: 40–325/2011(SR) dated 30.06.2011).