Miracle plant Moringa oleifera Lam.: nutritional, mineral, essential oil contents and biological activities

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Review Articles | Published:

DOI: 10.1007/s42535-024-01066-0
First Page: 867
Last Page: 874
Views: 1549

Keywords: Biological activity, Complementary medicine, Medicinal plants, n Moringan


Abstract


Since ancient times, humans have been able to employ several natural materials in the treatment of illness and injury thanks to the practice of complementary medicine. Many plants, animals, and fungi have proven effective in the treatment of sickness in humans. Among these natural resources, plants play a significant role. In our study, studies in the literature on Moringa oleifera Lam. were compiled. In this light, the plant’s nutritional and mineral composition, essential oil composition, and biological activity were gathered. Literature studies show that M. oleifera has significant nutrient and mineral concentrations and a wide range of potential applications. In addition to its high concentration of essential oils, it has been shown to possess a wide range of beneficial biological properties. M. oleifera is considered a valuable natural resource in this setting due to its potential use in alternative treatment.

Biological activity, Complementary medicine, Medicinal plants, n                     Moringan


References


Adeyi AO, Ajisebiola SB, Adeyi EO, Alimba CG, Okorie UG (2020) Antivenom activity of Moringa oleifera leave against pathophysiological alterations, somatic mutation and biological activities of Naja nigricollis venom. Sci Afr 8:e00356. https://doi.org/10.1016/j.sciaf.2020.e00356


Ajisebiola BS, Rotimi S, Anwar U, Adeyi AO (2021) Neutralization of Bitis arietans venom-induced pathophysiological disorder, biological activities and genetic alterations by Moringa oleifera leaves. Toxin Rev 40(4):847–858. https://doi.org/10.1080/15569543.2020.1793780


Anwar F, Latif S, Ashraf M, Gilani AH (2007) Moringa oleifera: a food plant with multiple medicinal uses. Phytother Res Int J Devoted Pharmacol Toxicol Eval Nat Prod Deriv 21(1):17–25. https://doi.org/10.1002/ptr.2023


Baba H, Sevindik M, Dogan M, Akgül H (2020) Antioxidant, antimicrobial activities and heavy metal contents of some Myxomycetes. Fresenius Environ Bull 29(09):7840–7846


Bal C, Sevindik M, Akgul H, Selamoglu Z (2019) Oxidative stress index and antioxidant capacity of Lepista nuda collected from Gaziantep/Turkey. Sigma J Eng Nat Sci 37(1):1–5


Barreto MB, Freitas JVBD, Silveira ER, Bezerra AME, Nunes EP, Gramosa NV (2009) Volatile and non-volatile chemical constituents of Moringa oleifera Lam., Moringaceae. Rev Bras Farmacogn 19:893–897. https://doi.org/10.1590/S0102-695X2009000600018


Bhadresha KP, Jain NK, Rawal RM (2022) Assessing the protective effect of Moringa oleifera extract against bone metastasis: an in vitro simulated digestion approach. Nutr Cancer 74(3):1023–1036. https://doi.org/10.1080/01635581.2021.1933099


Botero K, Alvarez-Yela C, Rivera L, Botero J, Gonzalez-Muñoz A, Gallego A, Arboleda-Valencia JW (2019) Morinpeptides: in silico identification of antimicrobial peptides and biological activity from Moringa oleifera leaves. Pharmacologyonline 2:199–211





Castillo-Lopez RI, Leon-Felix J, Angulo-Escalante MA, Gutierrez-Dorado R, Muy-Rangel MD, Heredia JB (2017) Nutritional and phenolic characterization of Moringa oleifera leaves grown in Sinaloa, Mexico. Pak J Bot 49(1):161–168


Das PE, Abu-Yousef IA, Majdalawieh AF, Narasimhan S, Poltronieri P (2020) Green synthesis of encapsulated copper nanoparticles using a hydroalcoholic extract of Moringa oleifera leaves and assessment of their antioxidant and antimicrobial activities. Molecules 25(3):555. https://doi.org/10.3390/molecules25030555


Eraslan EC, Altuntas D, Baba H, Bal C, Akgül H, Akata I, Sevindik M (2021) Some biological activities and element contents of ethanol extract of wild edible mushroom Morchella esculenta. Sigma J Eng Nat Sci 39(1):24–28


Fernandes Â, Bancessi A, Pinela J, Dias MI, Liberal Â, Calhelha RC, Barros L (2021) Nutritional and phytochemical profiles and biological activities of Moringa oleifera Lam. edible parts from Guinea-Bissau (West Africa). Food Chem 341:128229. https://doi.org/10.1016/j.foodchem.2020.128229


Fitriana WD, Ersam T, Shimizu K, Fatmawati S (2016) Antioxidant activity of Moringa oleifera extracts. Indones J Chem 16(3):297–301


Foidl N, Makkar HPS, Becker K (2001) The potential of Moringa oleifera for agricultural and industrial uses. What development potential for Moringa products 20.


Gupta R, Kannan GM, Sharma M, Flora SJ (2005) Therapeutic effects of Moringa oleifera on arsenic-induced toxicity in rats. Environ Toxicol Pharmacol 20(3):456–464. https://doi.org/10.1016/j.etap.2005.05.005


Hur SJ, Lee SY, Kim YC, Choi I, Kim GB (2014) Effect of fermentation on the antioxidant activity in plant-based foods. Food Chem 160:346–356. https://doi.org/10.1016/j.foodchem.2014.03.112


Hussein MA, Gobba NA, El Bishbishy MH (2014) Composition, in vitro antioxidant and antitumor properties of essential oil from the seeds of Moringa oleifera. Int J Pharm Scien 4:532–540


Ibok O, Deborah O (2008) Nutritional potential of two leafy vegetables: Moringa oleifera and Ipomoea batatas leaves. Sci Res Essays 3(2):057–060


Islek C, Saridogan BGO, Sevindik M, Akata I (2021) Biological activities and heavy metal contents of some Pholiota species. Fresenius Environ Bull 30(6):6109–6114


Jung IL (2014) Soluble extract from Moringa oleifera leaves with a new anticancer activity. PLoS ONE 9(4):e95492. https://doi.org/10.1371/journal.pone.0095492


Karthivashan G, Tangestani Fard M, Arulselvan P, Abas F, Fakurazi S (2013) Identification of bioactive candidate compounds responsible for oxidative challenge from hydro-ethanolic extract of Moringa oleifera leaves. J Food Sci 78(9):C1368–C1375. https://doi.org/10.1111/1750-3841.12233


Kasolo JN, Bimenya GS, Ojok L, Ochieng J, Ogwal-Okeng JW (2010) Phytochemicals and uses of Moringa oleifera leaves in Ugandan rural communities. J Med Plants Res 4(9):753–757. https://doi.org/10.5897/JMPR10.492


Kayode RMO, Afolayan AJ (2015) Cytotoxicity and effect of extraction methods on the chemical composition of essential oils of Moringa oleifera seeds. J Zhejiang Univ Sci B 16(8):680–689


Kekuda TP, Mallikarjun N, Swathi D, Nayana KV, Aiyar MB, Rohini TR (2010) Antibacterial and antifungal efficacy of steam distillate of Moringa oleifera Lam. J Pharm Sci Res 2(1):34


Khan J, Tousif MI, Saleem M, Nazir M, Touseef S, Saleem K, Qaisrani MM (2021) Insight into the phytochemical composition, biological activities and docking studies of Moringa oleifera Lam. to authenticate its use in biopharmaceutical industries. Ind Crops Prod 172:114042. https://doi.org/10.1016/j.indcrop.2021.114042


Korkmaz N, Dayangaç A, Sevindik M (2021) Antioxidant, antimicrobial and antiproliferative activities of Galium aparine. J Fac Pharm Ankara Univ 45(3):554–564


Krupodorova T, Sevindik M (2020) Antioxidant potential and some mineral contents of wild edible mushroom Ramaria stricta. AgroLife Sci J 9(1):186–191


Kumbhare MR, Guleha V, Sivakumar T (2012) Estimation of total phenolic content, cytotoxicity and in-vitro antioxidant activity of stem bark of Moringa oleifera. Asian Paci J Trop Dis 2(2):144–150. https://doi.org/10.1016/S2222-1808(12)60033-4


Lalas S, Athanasiadis V, Karageorgou I, Batra G, Nanos GD, Makris DP (2017) Nutritional characterization of leaves and herbal tea of Moringa oleifera cultivated in Greece. J Herbs Spices Med Plants 23(4):320–333


Lanjwani AH, Ghanghro AB, Khuhawar TMJ, Lanjwani MF (2021) Nutritional assessment and biological activity of Moringa oleifera: biological activitiy of Moringa oleifera. Biol Sci PJSIR 64(1):1–6


Leone A, Spada A, Battezzati A, Schiraldi A, Aristil J, Bertoli S (2016) Moringa oleifera seeds and oil: characteristics and uses for human health. Int J Mol Sci 17(12):2141


Maheshwaran G, Selvi MM, Muneeswari RS, Bharathi AN, Kumar MK, Sudhahar S (2021) Green synthesis of lanthanum oxide nanoparticles using Moringa oleifera leaves extract and its biological activities. Adv Powder Technol 32(6):1963–1971


Marrufo T, Nazzaro F, Mancini E, Fratianni F, Coppola R, De Martino L, De Feo V (2013) Chemical composition and biological activity of the essential oil from leaves of Moringa oleifera Lam. cultivated in Mozambique. Molecules 18(9):10989–11000. https://doi.org/10.3390/molecules180910989


Mbikay M (2012) Therapeutic potential of Moringa oleifera leaves in chronic hyperglycemia and dyslipidemia: a review. Front Pharmacol 3:24. https://doi.org/10.3389/fphar.2012.00024


Mbokane EM, Moyo NAG (2020) Effects of dietary levels of essential oil extracts from Moringa oleifera and Artemisia afra on kidney histology, haemato-immunological parameters and disease resistance in Clarias gariepinus. Aquac Res 51(1):410–425


Milla PG, Peñalver R, Nieto G (2021) Health benefits of uses and applications of Moringa oleifera in bakery products. Plants 10(2):318. https://doi.org/10.3390/plants10020318


Mishra G, Singh P, Verma R, Kumar S, Srivastav S, Jha KK, Khosa RL (2011) Traditional uses, phytochemistry and pharmacological properties of Moringa oleifera plant: an overview. Pharm Lett 3(2):141–164


Mohammed FS, Akgul H, Sevindik M, Khaled BMT (2018) Phenolic content and biological activities of Rhus coriaria var. zebaria. Fresenius Environ Bull 27(8):5694–5702


Mohammed FS, Karakaş M, Akgül H, Sevindik M (2019) Medicinal properties of Allium calocephalum collected from Gara Mountain (Iraq). Fresenius Environ Bull 28(10):7419–7426


Mohammed FS, Günal S, Pehlivan M, Doğan M, Sevindik M, Akgül H (2020a) Phenolic content, antioxidant and antimicrobial potential of endemic Ferulago platycarpa. Gazi Univ J Sci 33(4):670–677


Mohammed FS, Günal S, Şabik AE, Akgül H, Sevindik M (2020b) Antioxidant and antimicrobial activity of Scorzonera papposa collected from Iraq and Turkey. Kahramanmaraş Sütçü İmam Üniversitesi Tarım Ve Doğa Dergisi 23(5):1114–1118


Mohammed FS, Kına E, Sevindik M, Doğan M, Pehlivan M (2021a) Antioxidant and antimicrobial activities of ethanol extract of Helianthemum salicifolium (Cistaceae). IJNPR 12(3):459–462


Mohammed FS, Korkmaz N, Doğan M, Şabik AE, Sevindik M (2021b) Some medicinal properties of Glycyrrhiza glabra (Licorice). J Fac Pharm Ankara Univ 45(3):524–534


Mohammed FS, Pehlivan M, Sevindik E, Akgul H, Sevindik M, Bozgeyik I, Yumrutas O (2021c) Pharmacological properties of edible Asparagus acutifolius and Asparagus officinalis collected from North Iraq and Turkey (Hatay). Acta Aliment 50(1):136–143


Moyo B, Masika PJ, Hugo A, Muchenje V (2011) Nutritional characterization of Moringa (Moringa oleifera Lam.) leaves. Afr J Biotechnol 10(60):12925–12933


Mustafa R, El-Naggar EB, Svajdlenka E, Omran G, ELFiky F, El-Hawiet A (2021) Enhancement of phenolic content, antioxidant and cytotoxic activities of Moringa oleifera leaf and seed by suspension culture. Nat Prod Res 35(23):5233–5237. https://doi.org/10.1080/14786419.2020.1744137


Offor IF, Ehiri RC, Njoku CN (2014) Proximate nutritional analysis and heavy metal composition of dried Moringa oleifera leaves from Oshiri Onicha LGA, Ebonyi State, Nigeria. J Environ Sci Toxicol Food Technol 8(1):57–62


Oluduro AO (2012) Evaluation of antimicrobial properties and nutritional potentials of Moringa oleifera Lam. leaf in South-Western Nigeria. Malays J Microbiol 8(2):59–67


Otunola GA, Afolayan AJ (2018) Chemical composition, antibacterial and in vitro anti-inflammatory potentials of essential oils from different plant parts of Moringa oleifera lam. Am J Biochem Biotechnol 14(3):210–220


Popoola JO, Obembe OO (2013) Local knowledge, use pattern and geographical distribution of Moringa oleifera Lam. (Moringaceae) in Nigeria. J Ethnopharmacol 150(2):682–691. https://doi.org/10.1016/j.jep.2013.09.043


Razis AFA, Ibrahim MD, Kntayya SB (2014) Health benefits of Moringa oleifera. Asian Pac J Cancer Prev. https://doi.org/10.7314/APJCP.2014.15.20.8571


Saridogan BGO, Islek C, Baba H, Akata I, Sevindik M (2021) Antioxidant antimicrobial oxidant and elements contents of Xylaria polymorpha and X. hypoxylon (Xylariaceae). Fresenius Environ Bull 30(5):5400–5404


Schwikkard S, van Heerden FR (2002) Antimalarial activity of plant metabolites. Nat Prod Rep 19(6):675–692


Selamoglu Z, Sevindik M, Bal C, Ozaltun B, Sen İ, Pasdaran A (2020) Antioxidant, antimicrobial and DNA protection activities of phenolic content of Tricholoma virgatum (Fr.) P. Kumm. Biointerface Res Appl Chem 10(3):5500–5506


Sevindik M (2020) Antioxidant and antimicrobial capacity of Lactifluus rugatus and its antiproliferative activity on A549 cells. IJTK 19(2):423–427


Sevindik M (2021) Anticancer, antimicrobial, antioxidant and DNA protective potential of mushroom Leucopaxillus gentianeus (Quél.) Kotl. IJEB 59(05):310–315


Sevindik M, Akgul H, Pehlivan M, Selamoglu Z (2017) Determination of therapeutic potential of Mentha longifolia ssp. longifolia. Fresenius Environ Bull 26(7):4757–4763


Sultana S (2020) Nutritional and functional properties of Moringa oleifera. Metab Open 8:100061


Suphachai C (2014) Antioxidant and anticancer activities of Moringa oleifera leaves. J Med Plants Res 8(7):318–325


Tang TF, Liu XM, Ling M, Lai F, Zhang L, Zhou YH, Sun RR (2013) Constituents of the essential oil and fatty acid from Malania oleifera. Ind Crops Prod 43:1–5. https://doi.org/10.1016/j.indcrop.2012.07.003


Thurber MD, Fahey JW (2009) Adoption of Moringa oleifera to combat under-nutrition viewed through the lens of the “differential innovations” theory. Ecol Food Nutr 48:212–225. https://doi.org/10.1080/03670240902794598


Ugwu CE, Suru SM (2021) Medicinal plants with hepatoprotective potentials against carbon tetrachloride-induced toxicity: a review. Egypt Liver J 11(1):1–26


Unal O, Eraslan EC, Uysal I, Mohammed FS, Sevindik M, Akgul H (2022) Biological activities and phenolic contents of Rumex scutatus collected from Turkey. Fresenius Environ Bull 31(7):7341–7346


Valdez-Solana MA, Mejia-Garcia VY, Tellez-Valencia A, Garcia-Arenas G, Salas-Pacheco J, Alba-Romero JJ, Sierra-Campos E (2015) Nutritional content and elemental and phytochemical analyses of Moringa oleifera grown in Mexico. J Chem. https://doi.org/10.1155/2015/860381


Velázquez-Zavala M, Peón-Escalante IE, Zepeda-Bautista R, Jiménez-Arellanes MA (2016) Moringa (Moringa oleifera Lam.): potential uses in agriculture, industry and medicine. Rev Chapingo Ser Hortic 22(2):95–116. https://doi.org/10.5154/r.rchsh.2015.07.018


Wang TY, Li Q, Bi KS (2018) Bioactive flavonoids in medicinal plants: Structure, activity and biological fate. Asian J Pharm Sci 13(1):12–23


Yaméogo CW, Bengaly MD, Savadogo A, Nikiema PA, Traore SA (2011) Determination of chemical composition and nutritional values of Moringa oleifera leaves. Pak J Nutr 10(3):264–268


Yang M, Tao L, Kang XR, Li LF, Zhao CC, Wang ZL, Tian Y (2022) Recent developments in Moringa oleifera Lam polysaccharides: a review of the relationship between extraction methods, structural characteristics and functional activities. Food Chem X:100322. https://doi.org/10.1016/j.fochx.2022.100322

 


Author Information


Department of Biology, Faculty of Science, University of Zakho, Duhok, Iraq