Natural therapeutics against SARS CoV2: the potentiality and challenges

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Review Articles | Published:

Print ISSN : 0970-4078.
Online ISSN : 2229-4473.
Website:www.vegetosindia.org
Pub Email: contact@vegetosindia.org
Doi: 10.1007/s42535-022-00401-7
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Keywords: Covid-19, Natural medicine, Nutraceuticals, Plant metabolites, Therapeutics


Abstract


The incidence of the COVID-19 pandemic completely reoriented global socio-economic parameters and human civilization have experienced the worst situation in the recent past. The rapid mutation rates in viruses have continuously been creating emerging variants of concerns (VOCs) which devastated different parts of the world with subsequent waves of infection. Although, series of antiviral drugs and vaccines were formulated but cent percent effectiveness of these drugs is still awaited. Many of these drugs have different side effects which necessitate proper trial before release. Plants are the storehouse of antimicrobial metabolites which have also long been utilized as traditional medicines against different viral infections. Although, proper mechanism of action of these traditional medicines are unknown, they may be a potential source of effective anti-COVID drug for future implications. Advanced bioinformatic applications have opened up a new arena in predicting these repurposed drugs as a potential COVID mitigator. The present review summarizes brief accounts of the corona virus with their possible entry mechanism. This study also tries to classify different possible anti COVID-19 plant-derived metabolites based on their probable mode of action. This review will surely provide useful information on repurposed drugs to combat COVID-19 in this critical situation.



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Acknowledgements


The authors express sincere thanks to respected Editor of the journal and anonymous reviewers for suggestions to improve the quality of the manuscript.


Author Information


Bhar Anirban
Post Graduate Department of Botany, Ramakrishna Mission Vivekananda Centenary College, Kolkata, India
anirbanbhar06@gmail.com
Jain Akansha
Division of Plant Biology, Bose Institute, Kolkata, India
akansha007@rediffmail.com

Das Sampa
Division of Plant Biology, Bose Institute, Kolkata, India

sampa@jcbose.ac.in