Vegetos

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Review Articles | Published: 07 August, 2026

References

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Dalmonte T, Andreani G, Rudelli C, Isani G (2024) Efficacy of extracts of oleogum resin of boswellia in the treatment of knee osteoarthritis: a systematic review and meta-analysis. Phytother Res 38(12):5672–5689. https://doi.org/10.1002/ptr.8336


David JJ, Kandasamy R, Chatterjee S (2022) Development and evaluation of polymer drug delivery system (PDDS) for delivery of Boswellia seratta. Materiale Plastice 59(2):40–49. https://doi.org/10.37358/MP.22.2.5583


Dejonckheere CS, Scafa D, Käsmann L, Zeyen T, Potthoff A-L, Schäfer N, Weller J, Herrlinger U, Schneider M, Vatter H, Grosu A-L, Brehmer S, Giordano FA, Sarria GR, Gkika E, Layer JP (2025) Boswellia serrata for the management of radiation-induced cerebral edema and necrosis: a systematic meta-narrative review of clinical evidence. Adv Radiation Oncol 10(4):101732. https://doi.org/10.1016/j.adro.2025.101732


Duweb A, Schmiech M, Ulrich J, Abdel-Kahaar E, Pfeiffer M, Gaafary E, Barth M, Simmet H, T., Syrovets T (2025) Comparative analysis of micellar and native formulations of Boswellia serrata oleogum extracts in T-cell receptor-activated lymphocytes. Biomed Pharmacother 186:118009. https://doi.org/10.1016/j.biopha.2025.118009


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El Gaafary M, Büchele B, Syrovets T, Agnolet S, Schneider B, Schmidt CQ, Simmet T (2015) An α-Acetoxy-Tirucallic acid isomer inhibits akt/mtor signaling and induces oxidative stress in prostate cancer cells. J Pharmacol Exp Ther 352(1):33–42. https://doi.org/10.1124/jpet.114.217323


Finamore C, Festa C, Cammarota M, Spinelli L, Morretta E, Cassiano C, Monti MC, Marchianò S, Massa C, Moraca F, Lupia A, Catalanotti B, Fiorucci S, Zampella A, De Marino S (2025) Exploring Boswellia serrata triterpenes: a new frontier in leukemia inhibitory factor receptor modulation. ACS Omega 10(21):22269–22284. https://doi.org/10.1021/acsomega.5c03492


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Hosain NA, Ghosh R, Bryant DL, Arivett BA, Farone AL, Kline PC (2019) Isolation, structure elucidation, and immunostimulatory activity of polysaccharide fractions from Boswellia carterii frankincense resin. Int J Biol Macromol 133:76–85. https://doi.org/10.1016/j.ijbiomac.2019.04.059


Hüsch J, Gerbeth K, Fricker G, Setzer C, Zirkel J, Rebmann H, Schubert-Zsilavecz M, Abdel-Tawab M (2012) Effect of phospholipid-based formulations of Boswellia serrata extract on the solubility, permeability, and absorption of the individual boswellic acid constituents present. J Nat Prod 75(10):1675–1682. https://doi.org/10.1021/np300009w


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Jaroš P, Vrublevskaya M, Lokočová K, Michailidu J, Kolouchová I, Demnerová K (2022) Boswellia serrata extract as an antibiofilm agent against Candida spp. Microorganisms 10(1):171. https://doi.org/10.3390/microorganisms10010171


Joseph A, Abhilash MB, Mulakal JN, Madhavamenon KI (2024) Pharmacokinetics of a natural self-emulsifying reversible hybrid-hydrogel (N’SERH) formulation of full-spectrum Boswellia serrata oleo-gum resin extract: randomised double-blinded placebo-controlled crossover study. Biol Pharm Bull 47(9):1583–1593. https://doi.org/10.1248/bpb.b24-00306


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Kimmatkar N, Thawani V, Hingorani L, Khiyani R (2003) Efficacy and tolerability of Boswellia serrata extract in treatment of osteoarthritis of knee—a randomized double blind placebo controlled trial. Phytomedicine 10(1):3–7. https://doi.org/10.1078/094471103321648593


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Lim KM, Song JH, Lim EY, Kim G-D, Lee S-Y, Lee S-H, Lee DK, Cho Y-B, Shin HS (2025) Immunomodulatory effects of herbal extract mixture of Boswellia serrata, Commiphora myrrha, and propolis in a forced swimming-induced mouse model of immune dysfunction. Appl Food Res 5(1):100662. https://doi.org/10.1016/j.afres.2024.100662


Mahdian D, Abbaszadeh-Goudarzi K, Raoofi A, Dadashizadeh G, Abroudi M, Zarepour E, Hosseinzadeh H (2020) Effect of Boswellia species on the metabolic syndrome: a review. Iran J Basic Med Sci 23(11). https://doi.org/10.22038/ijbms.2020.42115.9957


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Mamatha K, Prabhakaran P, Syam Das S, Kanjoormana Aryan M, Thomas J (2025) A full-spectrum Boswellia serrata extract with enhanced bioavailability, and its co-delivered system with curcumin alleviate pain and stiffness associated with moderate spondylitis: a randomized double-blind, placebo-controlled, 3-arm study. Front Pharmacol 16:1577429. https://doi.org/10.3389/fphar.2025.1577429


Mehrzadi S, Tavakolifar B, Huseini HF, Mosavat SH, Heydari M (2018) The effects of Boswellia serrata gum resin on the blood glucose and lipid profile of diabetic patients: a double-blind randomized placebo-controlled clinical trial. J Evidence-Based Integr Med 23:2515690X18772728. https://doi.org/10.1177/2515690X18772728


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Moudgil KD, Venkatesha SH (2022) The anti-inflammatory and immunomodulatory activities of natural products to control autoimmune inflammation. Int J Mol Sci 24(1):95. https://doi.org/10.3390/ijms24010095


Mukhopadhyay N, Shukla A, Makhal PN, Kaki VR (2023) Natural product-driven dual COX-LOX inhibitors: overview of recent studies on the development of novel anti-inflammatory agents. Heliyon 9(3):e14569. https://doi.org/10.1016/j.heliyon.2023.e14569


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Phan H-V-T, Duong T-H, Pham D-D, Pham H-A, Nguyen V-K, Nguyen T-P, Nguyen H-H, Nguyen N-H, Sam-ang P, Phontree K, Sichaem J (2022) Design and synthesis of new lupeol derivatives and their α -glucosidase inhibitory and cytotoxic activities. Nat Prod Res 36(1):1–7. https://doi.org/10.1080/14786419.2020.1758095


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Ragab EA, El-Wahab A, Doghish MF, Salama AS, Eissa RM, N., Darwish SF (2024) The journey of boswellic acids from synthesis to pharmacological activities. Naunyn-Schmiedeberg’s Arch Pharmacol 397(3):1477–1504. https://doi.org/10.1007/s00210-023-02725-w


Rahman HS, Othman HH, Hammadi NI, Yeap SK, Amin KM, Samad A, N., Alitheen NB (2020) Novel drug delivery systems for loading of natural plant extracts and their biomedical applications. Int J Nanomed 15:2439–2483. https://doi.org/10.2147/IJN.S227805


Rashan L, Hakkim FL, Idrees M, Essa M, Velusamy T, Al-Baloshi M, Al-Bulushi B, Jabri A, Alrizeiki A, Guillemin M, G., Hasson A, S. S (2019) Boswellia gum resin and essential oils: potential health benefits —an evidence based review. Int J Nutr Pharmacol Neurol Dis 9(2):53. https://doi.org/10.4103/ijnpnd.ijnpnd_11_19





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Vaishnav V, Mahesh S, Kumar P (2019) Assessment of genetic structure of the endangered forest species Boswellia serrata population in central India. J Trop For Sci 31(2):200–210. https://doi.org/10.26525/jtfs2019.31.2.200210


Varia U, Joshi D, Jadeja M, Katariya H, Detholia K, Soni V (2022) Development and evaluation of ultradeformable vesicles loaded transdermal film of boswellic acid. Future J Pharm Sci 8(1):39. https://doi.org/10.1186/s43094-022-00428-2

 

Author Information

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Regional Ayurveda Research Institute (CCRAS, Ministry of AYUSH), Port Blair, India