Vegetos
(An International Journal of Plant Research & Biotechnology)
(eISSN: 2229-4473)
Phytochemical and pharmacological profiling from sporophylls of Isoetes coromandelina L. - leading to anti-inflammation studies
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Research Articles | Published: 27 March, 2026
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Keywords: n Isoetes coromandelinan , Mineral analysis, Phytochemical profile, Antioxidant, Anti-inflammatory, Antimicrobial assay
Abstract
Isoetes coromandelina L., an aquatic Pteridophyte from the family Isoetaceae, has a history of traditional use as a remedy for rheumatism, tuberculosis and spleen and liver diseases. The present study is the first to investigate the phytochemical and pharmacological profiling from sporophylls of I. coromandelina, focusing on anti-inflammatory potential. Mineral analysis confirmed the presence of essential elements including Ca, K, NO3 and PO4. Phytochemical screening revealed diverse bioactive compounds such as flavonoids (46.02 mg), tannins (27.94 mg), phenols (28.30 mg), terpenoids (12.6 mg), alkaloids (11.6 mg), coumarins (10.72 mg), fatty acids, gums, catechins, emodin and anthocyanins. UV–Vis, FTIR confirmed major metabolites while HPLC specifically identified flavonoids and phenolic compounds. Pharmacological assessments demonstrated strong antioxidant activity through DPPH and hydroxyl radical scavenging assays, along with, significant anti-inflammatory activity using the HRBC membrane stabilization method with comparable IC50 values to standard references. The plant extract also exhibited notable antimicrobial activity against Staphylococcus aureus (8.3 ± 0.3 mm) and Candida albicans (11.6 ± 0.4 mm). These findings supports the use of I. coromandeina as a natural source as anti-inflammatory factor in tribal and ethnomedicine and hence could be used for further pharmaceutical and therapeutic applications in future. Explorations are needed to fulfil the lacuna in this area to tap the potential medicinal uses of this plant.
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Author Information
PG and Research Department of Botany, Holy Cross College (Autonomous), Affiliated to Bharathidasan University, Tiruchirappalli, India