A concise review on microbial degradation of pesticides and organohalogen compounds: recent advances and current challenges

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E-ISSN: 2229-4473.
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DOI: 10.1007/s42535-025-01256-4
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Keywords: Biodegradation, Mineralization, Co-metabolism, Microbial degradation, Organohalides, Organophosphates


Abstract


The toxicity and obstinate nature of pesticide and organohalide compounds raise an alarming concern for the soil, water, and other biotic components in the environment. Water is contaminated by pesticide residue that seeps into the ground and stays in the soil. Utilizing microorganisms as a means of biodegrading these pesticides has proven to be a sensible tactic. Future advancements in the biodegradation of xenobiotic chemicals have a lot of potential owing to the exploitation of microorganisms and their ability to break down different pesticides. In contrast to other physical and chemical methods, microbial breakdown of pesticides is cost-effective and environmentally friendly. Pesticides serve as the main carbon source for microorganisms, and in some situations, with the aid of another substance known as co-metabolic, they use different extracellular and intracellular enzymes to metabolize pesticides. In the present article, a review of pesticide biodegrading studies and promising outcomes are comprehensively discussed. Pesticides and organohalides compounds and the feasibility of biological breakdown in the environment are explained in detail. This review also highlights the possible strategies and future perspectives to metabolize pesticides in the environment.

Biodegradation, Mineralization, Co-metabolism, Microbial degradation, Organohalides, Organophosphates


References


Aislabie J, Lloyd-Jones G (1995) A review of bacterial-degradation of pesticides. Soil Res 33:925–942. https://doi.org/10.1071/sr9950925


Ali M, Kazmi AA, Ahmed N (2014) Study on effects of temperature, moisture and pH in degradation and degradation kinetics of aldrin, endosulfan, lindane pesticides during full-scale continuous rotary drum composting. Chemosphere 102:68–75. https://doi.org/10.1016/j.chemosphere.2013.12.022


Al-Qurainy F, Abdel-Megeed A (2009) Phytoremediation and detoxification of two organophosphorous pesticides residues in riyadh area. World Appl Sci 13:987–998


Baghour M (2019) Algal Degradation of Organic Pollutants. In: Martínez LMT, Kharissova OV, Kharisov BI (eds) Handbook of ecomaterials. Springer International Publishing, Cham, pp 565–586


Bahi A, Sauvage S, Payraudeau S et al (2023) Process formulations and controlling factors of pesticide dissipation in artificial ponds: a critical review. Ecol Eng 186:106820. https://doi.org/10.1016/j.ecoleng.2022.106820


Bala S, Garg D, Thirumalesh BV et al (2022) Recent strategies for bioremediation of emerging pollutants: a review for a green and sustainable environment. Toxics 10:484. https://doi.org/10.3390/toxics10080484


Bhatt P, Huang Y, Zhan H, Chen S (2019) Insight into microbial applications for the biodegradation of pyrethroid insecticides. Front Microbiol. https://doi.org/10.3389/fmicb.2019.01778


Bose S, Kumar PS, Vo D-VN et al (2021) Microbial degradation of recalcitrant pesticides: a review. Environ Chem Lett 19:3209–3228. https://doi.org/10.1007/s10311-021-01236-5


Chamberlain E, Shi H, Wang T et al (2012) Comprehensive screening study of pesticide degradation via oxidation and hydrolysis. J Agric Food Chem 60:354–363. https://doi.org/10.1021/jf2033158


Chen H, He X, Rong X et al (2009) Adsorption and biodegradation of carbaryl on montmorillonite, kaolinite and goethite. Appl Clay Sci 46:102–108. https://doi.org/10.1016/j.clay.2009.07.006


Čolović MB, Krstić DZ, Lazarević-Pašti TD et al (2013) Acetylcholinesterase inhibitors: pharmacology and toxicology. Curr Neuropharmacol 11:315–335. https://doi.org/10.2174/1570159X11311030006


Ćwieląg-Piasecka I (2023) Soil organic matter composition and ph as factors affecting retention of carbaryl. Carbof Metolach Soil Mol 28:5552. https://doi.org/10.3390/molecules28145552


Dandie CE, Weber J, Aleer S et al (2010) Assessment of five bioaccessibility assays for predicting the efficacy of petroleum hydrocarbon biodegradation in aged contaminated soils. Chemosphere 81:1061–1068. https://doi.org/10.1016/j.chemosphere.2010.09.059


Debost-Legrand A, Warembourg C, Massart C et al (2016) Prenatal exposure to persistent organic pollutants and organophosphate pesticides, and markers of glucose metabolism at birth. Environ Res 146:207–217. https://doi.org/10.1016/j.envres.2016.01.005


Deng W, Lin D, Yao K et al (2015) Characterization of a novel β-cypermethrin-degrading Aspergillus niger YAT strain and the biochemical degradation pathway of β-cypermethrin. Appl Microbiol Biotechnol 99:8187–8198. https://doi.org/10.1007/s00253-015-6690-2


Fareed M, Kesavachandran CN, Pathak MK et al (2012) Visual disturbances with cholinesterase depletion due to exposure of agricultural pesticides among farm workers. Toxicol Environ Chem 94:1601–1609. https://doi.org/10.1080/02772248.2012.718780


Gonzalez JM, Aranda B (2023) Microbial growth under limiting conditions-future perspectives. Microorganisms 11:1641. https://doi.org/10.3390/microorganisms11071641


Gupta M, Mathur S, Sharma TK et al (2016) A study on metabolic prowess of Pseudomonas sp. RPT 52 to degrade imidacloprid, endosulfan and coragen. J Hazard Mater 301:250–258. https://doi.org/10.1016/j.jhazmat.2015.08.055


Hayatsu M, Mizutani A, Hashimoto M et al (2001) Purification and characterization of carbaryl hydrolase from Arthrobacter sp. RC100. FEMS Microbiol Lett 201:99–103. https://doi.org/10.1016/S0378-1097(01)00255-5


Hazell P, Wood S (2008) Drivers of change in global agriculture. Philos Trans R Soc Lond B Biol Sci 363:495–515. https://doi.org/10.1098/rstb.2007.2166


Huang Y, Xiao L, Li F et al (2018) Microbial degradation of pesticide residues and an emphasis on the degradation of cypermethrin and 3-phenoxy benzoic acid: a review. Molecules 23:2313. https://doi.org/10.3390/molecules23092313


Hugo HJ, Mouton C, Malan AP (2014) Accelerated microbial degradation of nematicides in vineyard and orchard soils. S Afr J Enol Vitic 35:157–167


Kah M, Brown CD (2006) Adsorption of Ionisable Pesticides in Soils. In: Ware GW, Whitacre DM, Albert LA et al (eds) Reviews of environmental contamination and toxicology: continuation of residue reviews. Springer, New York, pp 149–217


Kalyabina VP, Esimbekova EN, Kopylova KV, Kratasyuk VA (2021) Pesticides: formulants, distribution pathways and effects on human health—a review. Toxicol Rep 8:1179–1192. https://doi.org/10.1016/j.toxrep.2021.06.004


Kannan K, Ramu K, Kajiwara N et al (2005) Organochlorine pesticides, polychlorinated biphenyls, and polybrominated diphenyl ethers in irrawaddy dolphins from India. Arch Environ Contam Toxicol 49:415–420. https://doi.org/10.1007/s00244-005-7078-6


Kästner M, Nowak KM, Miltner A et al (2014) Classification and modelling of nonextractable residue (NER) formation of xenobiotics in soil—a synthesis. Crit Rev Environ Sci Technol 44:2107–2171. https://doi.org/10.1080/10643389.2013.828270


Kaur R, Mavi GK, Raghav S, Khan I (2019) Pesticides Classification and its Impact on Environment. Int J Curr Microbiol Appl Sci 8:1889–1897. https://doi.org/10.20546/ijcmas.2019.803.224


Kaur S, Samota MK, Choudhary M et al (2022) How do plants defend themselves against pathogens-Biochemical mechanisms and genetic interventions. Physiol Mol Biol Plants 28:485–504. https://doi.org/10.1007/s12298-022-01146-y





Kilonzi JM, Otieno S (2024) Degradation kinetics and physiological studies of organophosphates degrading microorganisms for soil bioremediation. Stress Biol 4:11. https://doi.org/10.1007/s44154-023-00138-6


Kokkinaki A, Kokkinakis M, Kavvalakis MP et al (2014) Biomonitoring of dialkylphosphate metabolites (DAPs) in urine and hair samples of sprayers and rural residents of Crete, Greece. Environ Res 134:181–187. https://doi.org/10.1016/j.envres.2014.07.012


Kushwaha M, Verma S, Chatterjee S (2016) Profenofos, an acetylcholinesterase-inhibiting organophosphorus pesticide: a short review of its usage, toxicity, and biodegradation. J Environ Qual 45:1478–1489. https://doi.org/10.2134/jeq2016.03.0100


Langlois BE, Collins JA, Sides KG (1970) Some factors affecting degradation of organochlorine pesticides by bacteria1. J Dairy Sci 53:1671–1675. https://doi.org/10.3168/jds.S0022-0302(70)86461-X


Laura M, Snchez-Salinas E, Olvera-Velona A, Luis J (2011) Pesticides in the environment: impacts and its biodegradation as a strategy for residues treatment. In: Stoytcheva M (ed) Pesticides—Formulations, Effects, Fate. InTech


Li S, Wang D, Du D et al (2019) Characterization of co-metabolic biodegradation of methyl tert-butyl ether by a Acinetobacter sp. strain. RSC Adv 9:38962. https://doi.org/10.1039/c9ra09507a


Lumniczky K, Impens N, Armengol G et al (2021) Low dose ionizing radiation effects on the immune system. Environ Int 149:106212. https://doi.org/10.1016/j.envint.2020.106212


Malghani S, Chatterjee N, Yu HX, Luo Z (2009a) Braz J Microbiol 40:893–900. https://doi.org/10.1590/S1517-83822009000400021. http://www.scielo.br/scielo.php?script=sci_abstract&pid=S1517-83822009000400021&lng=en&nrm=iso&tlng=en


Malhotra H, Kaur S, Phale PS (2021) Conserved metabolic and evolutionary themes in microbial degradation of carbamate pesticides. Front Microbiol. https://doi.org/10.3389/fmicb.2021.648868


Mercurio P, Flores F, Mueller JF et al (2014) Glyphosate persistence in seawater. Mar Pollut Bull 85:385–390. https://doi.org/10.1016/j.marpolbul.2014.01.021


Mohanan N, Montazer Z, Sharma PK, Levin DB (2020) Microbial and enzymatic degradation of synthetic plastics. Front Microbiol 11:580709. https://doi.org/10.3389/fmicb.2020.580709


Morant M, Bak S, Møller BL, Werck-Reichhart D (2003) Plant cytochromes P450: tools for pharmacology, plant protection and phytoremediation. Curr Opin Biotechnol 14:151–162. https://doi.org/10.1016/S0958-1669(03)00024-7


Moretto A, Colosio C (2013) The role of pesticide exposure in the genesis of Parkinson’s disease: epidemiological studies and experimental data. Toxicology 307:24–34. https://doi.org/10.1016/j.tox.2012.11.021


Mukherjee S, Gupta RD (2020) Organophosphorus nerve agents: types, toxicity, and treatments. J Toxicol 2020:3007984. https://doi.org/10.1155/2020/3007984


Olisah C, Okoh OO, Okoh AI (2020) Occurrence of organochlorine pesticide residues in biological and environmental matrices in Africa: a two-decade review. Heliyon 6:e03518. https://doi.org/10.1016/j.heliyon.2020.e03518


Ortiz-Hernández ML, Sánchez-Salinas E, Olvera-Velona A, Folch-Mallol JL (2011) Pesticides in the Environment: Impacts and Their Biodegradation as a Strategy for Residues Treatment, 24


Ortiz-Hernández ML, Sánchez-Salinas E, Dantán-González E, et al (2013) Pesticide Biodegradation: Mechanisms, Genetics and Strategies to Enhance the Process. In: Biodegradation—Life of Science. IntechOpen, Rijeka


Pailan S, Gupta D, Apte S et al (2015) Degradation of organophosphate insecticide by a novel Bacillus aryabhattai strain SanPS1, isolated from soil of agricultural field in Burdwan, West Bengal, India. Int Biodeterior Biodegrad 103:191–195. https://doi.org/10.1016/j.ibiod.2015.05.006


Parte SG, Mohekar AD, Kharat AS (2017) Microbial degradation of pesticide: a review. AJMR 11:992–1012. https://doi.org/10.5897/AJMR2016.8402


Pathak VM, Verma VK, Rawat BS et al (2022) Current status of pesticide effects on environment, human health and it’s eco-friendly management as bioremediation: a comprehensive review. Front Microbiol 13:962619. https://doi.org/10.3389/fmicb.2022.962619


Phuong NM, Chu NC, Van Thuan D, et al (2019) Novel removal of diazinon pesticide by adsorption and photocatalytic degradation of visible light-driven Fe-TiO2/Bent-Fe photocatalyst. J Chem. https://www.hindawi.com/journals/jchem/2019/2678927/. Accessed 26 Jan 2021


Qi Z, Miller GW, Voit EO (2014) Rotenone and paraquat perturb dopamine metabolism: a computational analysis of pesticide toxicity. Toxicology 315:92–101. https://doi.org/10.1016/j.tox.2013.11.003


Rajak P, Roy S, Ganguly A et al (2023) Agricultural pesticides – friends or foes to biosphere? J Hazard Mater Adv 10:100264. https://doi.org/10.1016/j.hazadv.2023.100264


Rajmohan KS, Chandrasekaran R, Varjani S (2020) A Review on occurrence of pesticides in environment and current technologies for their remediation and management. Indian J Microbiol 60:125–138. https://doi.org/10.1007/s12088-019-00841-x





Shah BA, Malhotra H, Papade SE et al (2024) Microbial degradation of contaminants of emerging concern: metabolic, genetic and omics insights for enhanced bioremediation. Front Bioeng Biotechnol. https://doi.org/10.3389/fbioe.2024.1470522


Sharma A, Kumar V, Shahzad B et al (2019) Worldwide pesticide usage and its impacts on ecosystem. SN Appl Sci 1:1446. https://doi.org/10.1007/s42452-019-1485-1


Singh DK (2008) Biodegradation and bioremediation of pesticide in soil: concept, method and recent developments. Indian J Microbiol 48:35–40. https://doi.org/10.1007/s12088-008-0004-7


Tao M, Adler PR, Larsen AE, Suh S (2020) Pesticide application rates and their toxicological impacts: why do they vary so widely across the US? Environ Res Lett 15:124049. https://doi.org/10.1088/1748-9326/abc650


Tudi M, Daniel Ruan H, Wang L et al (2021) Agriculture development, pesticide application and its impact on the environment. Int J Environ Res Public Health 18:1112. https://doi.org/10.3390/ijerph18031112


Udiković-Kolić N, Scott C, Martin-Laurent F (2012) Evolution of atrazine-degrading capabilities in the environment. Appl Microbiol Biotechnol 96:1175–1189. https://doi.org/10.1007/s00253-012-4495-0


Warner GR, Mourikes VE, Neff AM et al (2020) Mechanisms of action of agrochemicals acting as endocrine disrupting chemicals. Mol Cell Endocrinol 502:110680. https://doi.org/10.1016/j.mce.2019.110680


Weir KM, Sutherland TD, Horne I et al (2006) A single monooxygenase, ese, is involved in the metabolism of the organochlorides endosulfan and endosulfate in an Arthrobacter sp. Appl Environ Microbiol 72:3524–3530. https://doi.org/10.1128/AEM.72.5.3524-3530.2006


Wu J, Luan T, Lan C et al (2007) Removal of residual pesticides on vegetable using ozonated water. Food Control 18:466–472. https://doi.org/10.1016/j.foodcont.2005.12.011


Yang S-C, Lei M, Chen T-B et al (2010) Application of zerovalent iron (Fe0) to enhance degradation of HCHs and DDX in soil from a former organochlorine pesticides manufacturing plant. Chemosphere 79:727–732. https://doi.org/10.1016/j.chemosphere.2010.02.046






































































 


Author Information


School of Basic Science and Research, Sharda University, Noida, India